abstract：:Glutathione S-transferases are a family of multifunctional proteins involved in intracellular transport processes and drug detoxication. In rats, these enzymes are dimeric proteins, and exist as cytosolic and microsomal proteins. The affinity purified rat testicular glutathione S-transferases are comprised of four sub...

journal_title：Reproductive biomedicine online

authors： Thyagaraju K,Vasundhara K,Hemavathi B,Devi KN

更新日期：2004-01-01 00:00:00

abstract：:The uptake of prenatal diagnosis in 436 singleton and 146 twin pregnancies following assisted reproduction was compared with a matched group of spontaneous conceptions. The first and second trimester ultrasound examination included target fetal anatomic evaluation and screening by specific markers described for fetal ...

journal_title：Reproductive biomedicine online

authors： Geipel A,Berg C,Katalinic A,Ludwig M,Germer U,Diedrich K,Gembruch U

更新日期：2004-01-01 00:00:00

abstract：:Intracytoplasmic sperm injection (ICSI) provides an excellent outcome in a consistent manner, and is therefore used worldwide as a routine procedure. Since its introduction, few modifications have been made to its methodology. Recently, a combination of ICSI with micro-hole drilling by laser (LA-ICSI) of the zona pell...

journal_title：Reproductive biomedicine online

authors： Nagy ZP

更新日期：2003-12-01 00:00:00

abstract：:The effect of translocations on embryo development was evaluated and results were compared in terms of embryo development with those of embryos obtained from standard intracytoplasmic sperm injection (ICSI) cycles. In 23 translocation carriers with 34 cycles, fertilization, pronuclear morphology scoring (PMS), develop...

journal_title：Reproductive biomedicine online

authors： Findikli N,Kahraman S,Kumtepe Y,Donmez E,Biricik A,Sertyel S,Berkil H,Melil S

更新日期：2003-11-01 00:00:00

abstract：:Case reports reveal that clinicians applying preimplantation genetic diagnosis are increasingly confronted with requests by patients which they consider ethically problematic. These requests raise the question to what extent physicians share responsibility for the welfare of the future child. Two categories of situati...

journal_title：Reproductive biomedicine online

authors： Pennings G,Bonduelle M,Liebaers I

更新日期：2003-11-01 00:00:00

abstract：:Nuclei of mature mammalian spermatozoa are extraordinarily resistant to chemical and thermal injury. Additionally, decondensation of spermatozoa DNA can be accompanied by little or no visual changes of the sperm head. This study tested whether human spermatozoa could be recovered following several cycles of primer ext...

journal_title：Reproductive biomedicine online

authors： Dozortsev D,Serafim R,Cardoso JJ,Abdelmassih S,Nagy P,Diamond MP,Abdelmassih R

更新日期：2003-10-01 00:00:00

abstract：:Ejaculated spermatozoa, particularly in infertile men, have been shown to display morphological and biochemical features that are typical of an apoptotic phenotype in somatic cells. Deregulation of apoptosis is known to play roles in a number of disease processes, but roles for apoptosis in ejaculated spermatozoa and ...

journal_title：Reproductive biomedicine online

authors： Oehninger S,Morshedi M,Weng SL,Taylor S,Duran H,Beebe S

更新日期：2003-10-01 00:00:00

abstract：:Premature LH and progesterone surges are associated with different factors and hormonal modulators. The aim of the present study was (i) to investigate the clinical and laboratory factors and (ii) to highlight the importance of different stimulation protocols in associated premature LH and progesterone surges in intra...

journal_title：Reproductive biomedicine online

authors： Cunha-Filho JS,Kadoch J,Righini C,Fanchin R,Frydman R,Olivennes F

更新日期：2003-09-01 00:00:00

abstract：:A culture system has been developed for pieces of whole endometrium, comprising many different cell types. The system maintains the integrity of all compartments important for tissue function and allows functional studies of the human endometrium. Endometrial biopsy strips were collected from fertile women. The strips...

journal_title：Reproductive biomedicine online

authors： Stavreus-Evers A,Hovatta O,Eriksson H,Landgren BM

更新日期：2003-09-01 00:00:00

abstract：:Meiotic spindles tether the chromosomes of oocytes and have been found to be structurally abnormal in older women. Conventional methods to image the meiotic spindle, such as immunostaining or transmission electron microscopy, require prior fixation, so they cannot be used clinically, and their utility in developmental...

journal_title：Reproductive biomedicine online

authors： Keefe D,Liu L,Wang W,Silva C

更新日期：2003-07-01 00:00:00

abstract：:This is the first report of an intrauterine pregnancy following timed coitus, resulting from transperitoneal sperm and/or oocyte migration as the oocyte originated from an ectopic (undescended) ovary. The patient was treated in the infertility clinic after a history of primary infertility for 2 years. Diagnosis of a m...

journal_title：Reproductive biomedicine online

authors： Ombelet W,Deblaere K,Grieten M,Verswijvel G,Nijs M,Hinoul P,de Jonge E

更新日期：2003-07-01 00:00:00

abstract：:Poor response to ovarian stimulation for assisted reproduction treatment is a therapeutic challenge. Oocyte donation may be unacceptable to some patients, and many couples opt to continue with treatment despite low follicle numbers. Minimal data are available regarding conception rates in poor responders who elect to ...

journal_title：Reproductive biomedicine online

authors： Ulug U,Ben-Shlomo I,Turan E,Erden HF,Akman MA,Bahceci M

更新日期：2003-06-01 00:00:00

abstract：:Quantitative fluorescent PCR (QF-PCR) has been shown to be an accurate assay for the rapid prenatal diagnosis of chromosome disorders. The extra-embryonic coelom develops during week 4 of gestation and it can be aspirated from the following week, making coelocentesis the earliest possible method of prenatal diagnosis ...

journal_title：Reproductive biomedicine online

authors： Jauniaux E,Cirigliano V,Adinolfi M

更新日期：2003-06-01 00:00:00

abstract：:The dramatic increase in the incidence of high order multiple pregnancies that has occurred since the mid-1970s is due to three main factors: increasing female age at conception; increasing use of ovulation induction agents and the introduction of sophisticated assisted reproduction techniques. High order multiple pre...

journal_title：Reproductive biomedicine online

authors： Brinsden PR

更新日期：2003-04-01 00:00:00

abstract：:The process of implantation and trophoblast invasion is currently considered as the most limiting factor for the establishment of pregnancy. Molecular interactions at the embryo-maternal interface during the time of adhesion and subsequent invasion are crucial to the process of embryonic implantation. Both partners, t...

journal_title：Reproductive biomedicine online

authors： Herrler A,von Rango U,Beier HM

更新日期：2003-03-01 00:00:00

abstract：:Programmed cell death or apoptosis is an essential component of human ovarian function and development. During early fetal life approximately 7 x 10(6) oocytes are formed in the human ovary. However, the number of oocytes is dramatically reduced already before birth through apoptotic cell death. In reproductive life, ...

journal_title：Reproductive biomedicine online

authors： Vaskivuo TE,Tapanainen JS

更新日期：2003-01-01 00:00:00

abstract：:FSH exists as a family of isohormones exhibiting distinct oligosaccharide structures, and the released FSH isoform mixtures change during the follicular phase of the menstrual cycle. In addition, the pulsatile release of gonadotrophins seems to expose follicles to bursts of more less-acidic FSH isoforms and the follic...

journal_title：Reproductive biomedicine online

authors： Yding Andersen C

更新日期：2002-11-01 00:00:00

abstract：:Preimplantation genetic diagnosis (PGD) for chromosomal disorders is currently performed by interphase fluorescence in-situ hybridization (FISH) analysis. This technique is known to have limitations for detecting some translocations and complete karyotyping, so visualization of chromosomes in single cells is required ...

journal_title：Reproductive biomedicine online

authors： Verlinsky Y,Cieslak J,Evsikov S,Galat V,Kuliev A

更新日期：2002-11-01 00:00:00

abstract：:In human embryos, blastomeres differentiate into trophectoderm (TE) cells and inner cell mass (ICM) cells of blastocysts. Although morphologically indistinguishable, blastomeres at early cleavage stages are likely to undergo changes on a molecular level that make them destined to become ICM or TE cells. While the tran...

journal_title：Reproductive biomedicine online

authors： Hansis C,Grifo JA,Tang Y,Krey LC

更新日期：2002-09-01 00:00:00

abstract：:Bacterial culture of semen samples from 100 male partners in infertile couples revealed the presence of aerobic bacteria in 49 cases. Streptococcus faecalis (Enterococcus) was isolated from 53%, micrococci species from 20% and alpha-haemolytic streptococci from 16% of the infected samples. The incidence of oligozoospe...

journal_title：Reproductive biomedicine online

authors： Mehta RH,Sridhar H,Vijay Kumar BR,Anand Kumar TC

更新日期：2002-07-01 00:00:00

abstract：:The objective of this review is to analyse and integrate into a semi-historical background the alternative treatments available for the alleviation of infertility. Data are presented on their causes and success, using compilations of data reported in the literature along with personal experience. Results are expressed...

journal_title：Reproductive biomedicine online

authors： Da Motta EL,Serafini P

更新日期：2002-07-01 00:00:00

abstract：:Preimplantation genetic diagnosis (PGD) has recently been performed for inherited cancer predisposition determined by p53 tumour suppressor gene mutations, suggesting the usefulness of PGD for late onset disorders with genetic predisposition, including those caused by the germline mutations of other tumour suppressor ...

journal_title：Reproductive biomedicine online

authors： Verlinsky Y,Rechitsky S,Verlinsky O,Chistokhina A,Sharapova T,Masciangelo C,Levy M,Kaplan B,Lederer K,Kuliev A

更新日期：2002-05-01 00:00:00

abstract：:A great deal is now known about the migration of spermatozoa within the female reproductive tract, and how they interact with the oocyte and achieve fertilization in a variety of species. The process involves a series of complex features. It is a mixture of active and passive transport and active migration, with drast...

journal_title：Reproductive biomedicine online

authors： Croxatto HB

更新日期：2002-03-01 00:00:00

abstract：:The contemporary approach to ovarian stimulation for IVF treatment results in supraphysiological concentrations of steroids during the follicular and luteal phases of the menstrual cycle. These sex steroids act directly and indirectly to mature the endometrium, influencing receptivity for implantation. Corpus luteum f...

journal_title：Reproductive biomedicine online

authors： van der Gaast MH,Beckers NG,Beier-Hellwig K,Beier HM,Macklon NS,Fauser BC

更新日期：2002-01-01 00:00:00

abstract：:The 20th century witnessed the steady development of knowledge about reproductive physiology and endocrinology in animals and humans. These advances led to the identification of higher centres governing the ovary and its follicles. Effects of X-rays on the head and other agents, or excision of the pituitary gland, led...

journal_title：Reproductive biomedicine online

authors： Lunenfeld B

更新日期：2002-01-01 00:00:00

abstract：:Reproductive strategies for the human species have basically remained unaltered since Homo sapiens first appeared, probably in the valleys of Africa: males have always attempted to pass their genes to the largest feasible number of females, selecting those females capable of providing the best quality of oocytes; fema...

journal_title：Reproductive biomedicine online

authors： Benagiano G

更新日期：2002-01-01 00:00:00

abstract：:The ability of rabbit fibroblasts of different ages to be reprogrammed following nuclear transfer (NT) to aged recipient oocytes was evaluated. The rate of NT blastocysts reconstructed with presumptive G1 stage morula cells or fetal fibroblasts was significantly higher (41.5% and 51.4%) than was those of cloned embryo...

journal_title：Reproductive biomedicine online

authors： Galat V,Lagutina I,Mezina M,Prokofiev MI,Zakhartchenko V

更新日期：2002-01-01 00:00:00

abstract：:Endometrial receptivity is a prerequisite for blastocyst implantation. During receptivity, the hairy-like epithelial cell microvilli transiently fuse to a single flower-like membrane projection called the 'pinopode'. Scanning electron microscopy in sequential endometrial biopsies shows that pinopodes appear about 1 we...

journal_title：Reproductive biomedicine online

authors： Nikas G,Aghajanova L

更新日期：2002-01-01 00:00:00

abstract：:The transvaginal approach to tubo-ovarian surgery allows easy and direct access to the tubo-ovarian structures and the fossa ovarica without additional manipulation. In the absence of a panoramic view, the proximity of the tubo-ovarian structures allows operative procedures for treatment of superficial and cystic ovar...

journal_title：Reproductive biomedicine online

authors： Gordts S,Campo R,Brosens I

更新日期：2002-01-01 00:00:00

abstract：:What makes reproductive technology unique is that it is in the forefront of creating human life, with an emphasis on 'giving'. Not surprisingly therefore, a significant appeal to altruism has crept into the language of reproductive technologies. If altruistic donations and behaviour involving reproductive technologies...

journal_title：Reproductive biomedicine online

authors： Bahadur G

更新日期：2001-01-01 00:00:00

abstract：:The fact that today it is possible to write a comprehensive report on assisted reproduction technologies in Latin America is the result of a serious and systematic effort, accomplished by more than 80 centres, from Mexico to Chile. Over the past 10 years, these centres representing the vast majority of assisted reprod...

journal_title：Reproductive biomedicine online

authors： Zegers-Hochschild F,Mackenna A,Fernández E,Sepúlveda MS

更新日期：2001-01-01 00:00:00

abstract：:Long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD) deficiency is a fatal autosomal recessive metabolic disorder, presenting during infancy. Preimplantation genetic diagnosis (PGD) provides an option for establishing an unaffected pregnancy, avoiding the risk for termination of pregnancy following prenatal diagnosis. T...

journal_title：Reproductive biomedicine online

authors： Verlinsky Y,Rechitsky S,Verlinsky O,Strom C,Kuliev A

更新日期：2001-01-01 00:00:00

abstract：:This prospective, observational study investigated the efficacy and tolerability of follitropin-alfa for ovarian stimulation in routine clinical practice. The study involved a large, unselected population of women. Stimulation parameters and treatment outcomes were documented for 767 patients who underwent a total of ...

journal_title：Reproductive biomedicine online

authors： Katzorke T,Verhoeven HC,Blechschmidt J,Köhler M,Kelly E

更新日期：2001-01-01 00:00:00

abstract：:Modern contraception is considered to be one the major advances of the 20th century. Yet, as the next century begins, it is estimated that there is still a largely unmet need for contraception, with millions of couples worldwide who express a wish to limit the number of their children but do not use or are not satisfi...

journal_title：Reproductive biomedicine online

authors： D'Arcangues C

更新日期：2001-01-01 00:00:00